Entry Detail


General Information

Database ID:exR0513999
RNA Name:DDOST
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):20651767End Site(bp):20661544
External Links:ENSG00000244038



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF1
chr6
30571393
30597179
+
ABHD14B
chr3
51968510
51983409
-
ABO
chr9
133250401
133276024
-
AC007192.1
chr19
18153158
18178117
+
AC024592.3
chr19
5866171
5903787
-
AC104452.1
chr3
49416777
49429314
-
AC104581.2
chr17
7925931
7930622
-
AC118549.1
chr1
77562416
77683419
-
ACACA
chr17
37084992
37406836
-
ACAP3
chr1
1292390
1309609
-
ACTG1
chr17
81509971
81523847
-
ADAM23
chr2
206443532
206621127
+
ADAMTS19
chr5
129460281
129738683
+
ADD3
chr10
109996368
110135565
+
ADSL
chr22
40346500
40390463
+
AGFG1
chr2
227472152
227561214
+
AGPAT5
chr8
6708642
6761503
+
AHCYL2
chr7
129225023
129430211
+
AL022238.4
chr22
40346529
40410054
+
AL121594.1
chr14
35122549
35317474
+
AL136295.4
chr14
24180395
24190416
-
ALDH1B1
chr9
38392702
38398661
+
ALDH9A1
chr1
165662216
165698863
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC067930.1
chr8
143579636
143580670
+
AC092490.1
chr12
8788253
8795789
+
AC106864.1
chr4
112693047
112706810
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.