exRNAdisease

Entry Detail

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General Information

Database ID: exR0514945 RNA Name: FAM102A RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 127940582 End Site(bp): 127980989 External Links: ENSG00000167106

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE36936 Description: Gene Expression in the Human Mammary Epithelium during Initiation of Lactation. Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: 12h post delivery Control Sample: 6h post delivery Number of Case: 7 Number of Control: 7 Number of Samples: 14

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACADVL chr17 7217125 7225266 + AHCY chr20 34280268 34311802 - AKAP1 chr17 57085092 57121346 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-17-5p chr13 91350618 91350640 + hsa-miR-28-5p chr3 188688794 188688815 + hsa-miR-122-5p chr18 58451088 58451109 + hsa-miR-124-3p chr8 64379210 64379231 + hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-302c-3p chr4 112648366 112648388 - hsa-miR-20b-5p chrX 134169850 134169872 - hsa-miR-485-5p chr14 101055427 101055448 + hsa-miR-520a-5p chr19 53690895 53690915 + hsa-miR-519b-3p chr19 53695263 53695284 + hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-625-5p chr14 65471116 65471136 + hsa-miR-650 chr22 22822791 22822811 + hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-193a-5p chr17 31560016 31560037 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-574-5p chr4 38868056 38868078 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-708-5p chr11 79402077 79402099 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22649065 Title: Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans Author: Mohammad MA, Hadsell DL, Haymond MW. Journal: Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76. Description: We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.