Entry Detail


General Information

Database ID:exR0722137
RNA Name:TMBIM6
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):49707725End Site(bp):49764934
External Links:ENSG00000139644



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AKAP12
chr6
151239967
151358559
+
AGA
chr4
177430774
177442437
-
ACTB
chr7
5527148
5563784
-
AATF
chr17
36948954
37056871
+
ACBD5
chr10
27195214
27242130
-
ADAMTS1
chr21
26835755
26845409
-
AL353588.1
chr6
44273194
44378957
+
AC092647.5
chr7
55887277
55955239
+
AC026464.4
chr16
69299682
69322700
+
AGO2
chr8
140520156
140635633
-
ABCG2
chr4
88090150
88231628
-
AFF1
chr4
86935002
87141054
+
AC004997.1
chr22
30285238
30299482
-
AL139353.1
chr14
31334312
31457441
-
AC048338.1
chr12
122207779
122266423
-
AIF1L
chr9
131096476
131123152
+
AC078927.1
chr12
66123917
66169985
-
ACSF2
chr17
50426158
50474845
+
ADAM22
chr7
87934143
88202889
+
ABHD8
chr19
17292131
17310236
-
ALDOA
chr16
30064164
30070457
+
ACTG1
chr17
81509971
81523847
-
AHCY
chr20
34280268
34311802
-
ACO2
chr22
41469117
41528989
+
AC010422.3
chr19
12643831
12648397
-
AASDHPPT
chr11
106075501
106098699
+
ACTL6A
chr3
179562886
179588407
+
AL162417.1
chr9
133098121
133163914
-
AHNAK
chr11
62433542
62556235
-
ADRM1
chr20
62302093
62308862
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009446.1
chr8
71675300
71702786
+
AC012360.3
chr2
105334027
105337475
-
AC018521.1
chr17
47945424
47981736
+
AC020978.7
chr16
68224713
68227734
+
AC022140.1
chr5
25404733
25445925
-
AC023509.1
chr12
53441741
53467528
+
AD000090.1
chr19
35557956
35581954
+
AF129075.2
chr21
29058073
29060095
-
AL021707.3
chr22
38734730
38738990
+
AL049543.1
chr6
28587378
28591747
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.