Entry Detail


General Information

Database ID:exR0722815
RNA Name:TUBB2B
RNA Type:mRNA
Chromosome:chr6
Starnd:-
Coordinate:
Start Site(bp):3224277End Site(bp):3231730
External Links:ENSG00000137285



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
AC011462.1
chr19
41350853
41425001
+
AC018523.2
chr11
14493783
14520344
-
AC092143.1
chr16
89919165
89936092
+
AC093525.2
chr16
2496032
2520218
+
AC138894.1
chr16
28456371
28492098
-
AC245033.1
chr15
82536788
82573194
-
ACTB
chr7
5527148
5563784
-
ACTR1A
chr10
102461881
102502712
-
ADD3
chr10
109996368
110135565
+
ADIPOR1
chr1
202940826
202958572
-
AKR1A1
chr1
45550543
45570049
+
AKR1E2
chr10
4786629
4848062
+
AL022238.4
chr22
40346529
40410054
+
AL121758.1
chr20
646626
675800
-
ALCAM
chr3
105366909
105576900
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-92a-3p
chrX
134169544
134169565
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079781.5
chr7
97851688
97972985
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.