Entry Detail


General Information

Database ID:exR0723163
RNA Name:VCP
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):35056064End Site(bp):35072627
External Links:ENSG00000165280



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AACS
chr12
125065434
125143333
+
ABHD12
chr20
25294742
25390835
-
AC005258.1
chr19
2269525
2341172
+
AC010422.3
chr19
12643831
12648397
-
AC073896.1
chr12
56285916
56316059
-
AC091167.2
chr15
90249556
90272208
+
AC093525.2
chr16
2496032
2520218
+
ACADS
chr12
120725774
120740008
+
ACBD6
chr1
180269653
180502954
-
ACTG1
chr17
81509971
81523847
-
ADAR
chr1
154582057
154628013
-
ADH5
chr4
99070978
99088801
-
AL121753.1
chr20
35267885
35280043
-
ALDH2
chr12
111766887
111817532
+
ALDH7A1
chr5
126531200
126595362
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-331-3p
chr12
95308480
95308500
+
hsa-miR-339-5p
chr7
1022990
1023012
-
hsa-miR-520a-5p
chr19
53690895
53690915
+
hsa-miR-450b-5p
chrX
134540231
134540252
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002310.1
chr16
30534752
30537149
+
AC112484.1
chr3
128860620
128871540
-
AC132217.1
chr11
2129121
2129964
-
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL031282.2
chr1
1702736
1737688
-
AL121992.1
chr1
15586136
15603626
-
AL135925.1
chr10
79825902
79827602
+
AL136985.3
chr1
58715609
58771295
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.