Entry Detail


General Information

Database ID:exR0723787
RNA Name:ZNF354B
RNA Type:mRNA
Chromosome:chr5
Starnd:+
Coordinate:
Start Site(bp):178859953End Site(bp):178888122
External Links:ENSG00000178338



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008982.1
chr19
38817471
38840178
-
AC009690.3
chr15
72266746
72319946
-
AC093668.1
chr7
102541501
102592444
-
ACAD9
chr3
128879596
128916067
+
ACLY
chr17
41866917
41930542
-
ACSF3
chr16
89088375
89164121
+
ACTB
chr7
5527148
5563784
-
ACTR1A
chr10
102461881
102502712
-
ADAM15
chr1
155050566
155062775
+
ADAM19
chr5
157395534
157575775
-
ADARB1
chr21
45073853
45226560
+
ADD2
chr2
70607618
70768225
-
ADSL
chr22
40346500
40390463
+
AHCY
chr20
34280268
34311802
-
AHCYL1
chr1
109984765
110023742
+
AIF1L
chr9
131096476
131123152
+
AKAP13
chr15
85380571
85749358
+
AKT2
chr19
40230317
40285536
-
AL021546.1
chr12
120438198
120460006
+
AL022238.4
chr22
40346529
40410054
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4517
chr16
28958587
28958611
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC005899.4
chr17
32328441
32329395
+
AC007952.4
chr17
19112000
19112636
-
AC011445.1
chr19
39314651
39320858
-
AC067930.1
chr8
143579636
143580670
+
AC084082.1
chr8
66112667
66126632
+
AC144548.1
chr12
110387463
110445548
-
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL117378.1
chr6
131901963
131920565
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.