exRNAdisease

Entry Detail

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General Information

Database ID: exR0749449 RNA Name: hsa-let-7e-5p RNA Type: miRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 51692793 End Site(bp): 51692814 External Links: hsa-let-7e-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARHGAP28 chr18 6729718 6915716 + BACH1 chr21 29194071 29630751 + BCAM chr19 44809071 44821421 + BLOC1S6 chr15 45587214 45615945 + C15orf41 chr15 36579626 36810248 + C19orf53 chr19 13774456 13778773 + COIL chr17 56938199 56961050 - CTPS2 chrX 16587999 16712936 - GRPEL2 chr5 149345430 149354583 + HDLBP chr2 241227264 241317061 - HMGA1 chr6 34236873 34246231 + IGDCC3 chr15 65327127 65378002 - IGF2BP1 chr17 48997385 49056145 + MNT chr17 2384073 2401104 - MPDZ chr9 13105704 13279590 - OPA3 chr19 45527427 45602212 - PACS1 chr11 66070272 66244744 + PDPR chr16 70113626 70162537 + PHC3 chr3 170086732 170181749 - PLD3 chr19 40348456 40380439 + PLPP6 chr9 4662294 4665258 + PPARA chr22 46150521 46243756 + RAB40C chr16 589357 629272 + RANBP2 chr2 108719482 108785809 + SH3PXD2B chr5 172325000 172454525 - TECPR2 chr14 102362941 102502477 + TNRC6B chr22 40044817 40335808 + TRIM65 chr17 75880335 75896951 - UBE2G2 chr21 44768580 44801826 - YOD1 chr1 207043849 207052980 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000247 chr10 74474868 74475660 + hsa_circ_0000987 chr2 30748452 30756180 + hsa_circ_0000246 chr10 74468040 74475660 + hsa_circ_0000018 chr1 15860731 15863309 + hsa_circ_0000038 chr1 28800065 28802803 + hsa_circ_0000799 chr17 65941524 65972074 + hsa_circ_0001164 chr20 45891031 45923523 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.5 chr12 6510275 6510522 + AC074117.1 chr2 27356246 27367622 + AC109460.3 chr16 28974804 28990775 + AC124045.1 chr3 44667412 44669364 + AP000766.1 chr11 107312132 107316271 - ARHGAP27P1-BPTFP1-KPNA2P3 chr17 64749663 64781707 - KCNQ1OT1 chr11 2608328 2699994 - LINC00265 chr7 39733430 39793092 + LINC02381 chr12 54126082 54147485 + MIRLET7BHG chr22 46053869 46113928 + NEAT1 chr11 65422774 65445540 + NUTM2A-AS1 chr10 87201647 87342612 - SNHG16 chr17 76557764 76565348 + SNHG4 chr5 139274102 139284899 + TMPO-AS1 chr12 98512973 98516422 - XIST chrX 73820649 73852723 - ZNF436-AS1 chr1 23368997 23371839 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.