exRNAdisease

Entry Detail

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General Information

Database ID: exR0749519 RNA Name: hsa-miR-148a-3p RNA Type: miRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 25949922 End Site(bp): 25949943 External Links: hsa-miR-148a-3p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CD151 chr11 832887 839831 + DYRK1A chr21 37365573 37526358 + E2F1 chr20 33675477 33686385 - EMP1 chr12 13196723 13219941 + FAM47E-STBD1 chr4 76251721 76311129 + KLF4 chr9 107484852 107490482 - LENG8 chr19 54448887 54462037 + LYSMD2 chr15 51723011 51751585 - LYSMD4 chr15 99715697 99733561 - MLPH chr2 237485428 237555322 + MTMR9 chr8 11284816 11328146 + NDST1 chr5 150485818 150558211 + NFE2L1 chr17 48048329 48061545 + OSBPL11 chr3 125528858 125595497 - PFAS chr17 8247618 8270491 + PGRMC1 chrX 119236245 119244466 + RC3H1 chr1 173931084 174022357 - RNF145 chr5 159157409 159210053 - RTN4 chr2 54972187 55112621 - SELENON chr1 25800176 25818221 + STARD13 chr13 33103137 33350630 - STBD1 chr4 76306026 76311599 + SYVN1 chr11 65121780 65134533 - TBC1D5 chr3 17157162 18444817 - TMF1 chr3 69019827 69052339 - TOMM70 chr3 100363431 100401089 - TRIM3 chr11 6448613 6474459 - VPS45 chr1 150067279 150145329 + ZNF512B chr20 63956704 63969930 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001454 chr4 154524454 154533552 + hsa_circ_0000384 chr12 27867712 27877119 + hsa_circ_0000284 chr11 33307958 33309057 + hsa_circ_0000943 chr19 47421744 47440665 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007780.1 chr17 68413623 68524949 + AC073896.4 chr12 56162359 56190284 - AL049840.4 chr14 103694516 103695050 - AL603839.3 chr1 40493157 40508661 - H19 chr11 1995176 2001470 - HCG18 chr6 30286690 30327382 - KCNQ1OT1 chr11 2608328 2699994 - LINC01089 chr12 121795267 121803906 - NEAT1 chr11 65422774 65445540 + NUTM2A-AS1 chr10 87201647 87342612 - NUTM2B-AS1 chr10 79661394 79826594 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.