exRNAdisease

Entry Detail

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General Information

Database ID: exR0749547 RNA Name: hsa-miR-182-5p RNA Type: miRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 129770447 End Site(bp): 129770470 External Links: hsa-miR-182-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BCL11A chr2 60450520 60554467 - CTDSP2 chr12 57819927 57846729 - EVI5 chr1 92508696 92792404 - KHSRP chr19 6413348 6424794 - PAN2 chr12 56316223 56334053 - PKN2 chr1 88684222 88836255 + PLXNA1 chr3 126988594 127037392 + PRLR chr5 35048756 35230487 - RPS29 chr14 49570984 49599164 - SDCBP chr8 58552924 58582859 + SLC30A1 chr1 211571568 211579161 - ZNF189 chr9 101398873 101410660 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001728 chr7 99695763 99695845 - hsa_circ_0001409 chr4 48835417 48859382 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005034.3 chr2 75697583 75697996 + AC018521.1 chr17 47945424 47981736 + AC091564.7 chr11 6610883 6616594 - AL137129.1 chr14 61734138 61776260 + HAGLR chr2 176164051 176188958 - KCNQ1OT1 chr11 2608328 2699994 - LAMTOR5-AS1 chr1 110347116 110443817 + NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - SNHG1 chr11 62851984 62855953 - SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.