exRNAdisease

Entry Detail

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General Information

Database ID: exR0749576 RNA Name: hsa-miR-199b-5p RNA Type: miRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 128244783 End Site(bp): 128244805 External Links: hsa-miR-199b-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH3B2 chr11 67662160 67681224 - ATP9A chr20 51596514 51768390 - CHD2 chr15 92900189 93027996 + COL4A2 chr13 110305812 110513209 + COX6A1 chr12 120438090 120440737 + FAM222B chr17 28755978 28855232 - FOSL2 chr2 28392448 28417317 + HMGCS1 chr5 43287470 43313512 - KRT80 chr12 52168996 52192014 - MYRF chr11 61752642 61788518 + NFE2L1 chr17 48048329 48061545 + SLC7A5 chr16 87830023 87869507 - WNT5A chr3 55465715 55490539 - XPO6 chr16 28097979 28211920 - ZMIZ1 chr10 79068966 79316528 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000591 chr15 41961025 41962156 + hsa_circ_0001005 chr2 53921020 53978078 - hsa_circ_0000892 chr19 11941431 12014514 + hsa_circ_0000931 chr19 38226804 38231095 - lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004951.4 chr7 43951910 44019151 - AC095055.1 chr4 151139991 151141103 + BX284668.2 chr1 16870945 16883659 + LINC01783 chr1 16533886 16536172 - POLR2J4 chr7 43940895 44019175 - SNHG12 chr1 28578538 28583132 - TMPO-AS1 chr12 98512973 98516422 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.