exRNAdisease

Entry Detail

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General Information

Database ID: exR0755170 RNA Name: SNHG7 RNA Type: lncRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 136721366 End Site(bp): 136728184 External Links: ENSG00000233016

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005670.2 chr17 46923133 47049932 + AC245033.1 chr15 82536788 82573194 - ACO2 chr22 41469117 41528989 + AD000671.1 chr19 35745678 35754519 + ADARB1 chr21 45073853 45226560 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-181a-5p chr1 198859108 198859130 - hsa-miR-181b-5p chr9 124693725 124693747 + hsa-miR-181c-5p chr19 13874725 13874746 + hsa-miR-122-5p chr18 58451088 58451109 + hsa-miR-9-5p chr5 88666902 88666924 - hsa-miR-186-5p chr1 71067681 71067702 - hsa-miR-34b-5p chr11 111512950 111512972 + hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-342-3p chr14 100109715 100109737 + hsa-miR-331-3p chr12 95308480 95308500 + hsa-miR-449a chr5 55170586 55170607 - hsa-miR-181d-5p chr19 13874910 13874932 + hsa-miR-625-5p chr14 65471116 65471136 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-653-5p chr7 93482823 93482843 - hsa-miR-425-5p chr3 49020199 49020221 - hsa-miR-214-5p chr1 172138857 172138878 - hsa-miR-574-5p chr4 38868056 38868078 + hsa-miR-543 chr14 101032033 101032054 + hsa-miR-216b-5p chr2 56000764 56000785 - hsa-miR-941 chr20 63919551 63919573 + hsa-miR-449c-5p chr5 55172313 55172337 - hsa-miR-2682-5p chr1 98045307 98045329 - hsa-miR-3186-3p chr17 81451116 81451136 - hsa-miR-4262 chr2 11836943 11836959 - hsa-miR-4436a chr2 88812425 88812445 + hsa-miR-5000-3p chr2 75090873 75090894 + hsa-miR-506-5p chrX 147230788 147230809 - hsa-miR-579-5p chr5 32394430 32394451 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020663.1 chr16 4730115 4752565 - AC020978.7 chr16 68224713 68227734 + AC074183.1 chr7 84939349 84940245 - AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.