exRNAdisease

Entry Detail

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General Information

Database ID: exR0807489 RNA Name: MALAT1 RNA Type: lncRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 65497688 End Site(bp): 65506516 External Links: ENSG00000251562

Disease Information

Disease Name: Colorectal Cancer Disease Category: Cancers MeSH ID: D003110 Type: Neoplasms/Digestive System Neoplasms Alias: Colonic Neoplasms//Colonic Neoplasm//Neoplasm, Colonic//Neoplasms, Colonic//Colon Neoplasms//Colon Neoplasm//Neoplasm, Colon//Neoplasms, Colon//Cancer of Colon//Colon Cancers//Cancer of the Colon//Colonic Cancer//Cancer, Colonic//Cancers, Colonic//Colonic Cancers//Colon Cancer//Cancer, Colon//Cancers, Colon

Expression Detail

GEO ID: GSE71008 Description: Plasma extracellular RNA profiles in healthy and cancer patients Experimental Design: Cancer vs Control Case Disease Type: Colorectal Cancer Case Disease SubType: NA Case Sample: Colorectal Cancer Control Sample: Healthy Number of Case: 100 Number of Control: 50 Number of Samples: 150

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AL157392.5 chr10 13610047 13655929 + ADIPOR1 chr1 202940826 202958572 - ABR chr17 1003518 1229738 - ABT1 chr6 26596953 26600739 + ABCD4 chr14 74285269 74303055 - ADD3 chr10 109996368 110135565 + AC007192.1 chr19 18153158 18178117 + AL133352.1 chr10 100505628 100529881 - ADIPOR2 chr12 1688574 1788674 + AL136295.1 chr14 24189157 24213473 - ACTA2 chr10 88935074 88991339 - ACTG1 chr17 81509971 81523847 - AC073508.2 chr17 40627356 40665141 - ACBD6 chr1 180269653 180502954 - AL021546.1 chr12 120438198 120460006 + ACTR3 chr2 113890063 113962596 + ADO chr10 62804720 62808479 + AC068946.2 chr2 219209772 219222738 - AGPAT5 chr8 6708642 6761503 + AC068580.4 chr11 1734821 1763954 - AK2 chr1 33007940 33080996 - ACTB chr7 5527148 5563784 - AL136295.4 chr14 24180395 24190416 - AKR1A1 chr1 45550543 45570049 + AKR7A2 chr1 19303965 19312146 - AL358113.1 chr9 69035747 69255187 + ALCAM chr3 105366909 105576900 + ACOT8 chr20 45841721 45857405 - ADAT1 chr16 75596981 75623300 - AC124312.1 chr15 24955034 25000276 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1913 chr6 166509364 166509385 - hsa-miR-3146 chr7 19705366 19705387 - hsa-miR-3690 chrY 1293927 1293949 + hsa-miR-519e-5p chr19 53679953 53679974 + hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-9-3p chr15 89368071 89368092 + hsa-miR-493-5p chr14 100869075 100869096 + hsa-miR-205-5p chr1 209432166 209432187 + hsa-miR-199b-3p chr9 128244745 128244766 - hsa-miR-876-5p chr9 28863675 28863696 - hsa-miR-3611 chr10 35079609 35079629 - hsa-miR-181c-5p chr19 13874725 13874746 + hsa-miR-422a chr15 63870989 63871010 - hsa-miR-498-5p chr19 53674230 53674252 + hsa-miR-519d-3p chr19 53713400 53713421 + hsa-miR-3129-5p chr2 189133082 189133103 - hsa-miR-370-3p chr14 100911186 100911207 + hsa-miR-20a-5p chr13 91351072 91351094 + hsa-miR-3200-3p chr22 30731610 30731631 + hsa-miR-6746-3p chr11 61878216 61878237 - hsa-miR-22-3p chr17 1713914 1713935 - hsa-miR-4739 chr17 79707216 79707240 - hsa-miR-539-3p chr14 101047369 101047390 + hsa-miR-106a-5p chrX 134170244 134170266 - hsa-miR-105-5p chrX 152394458 152394480 - hsa-miR-3622a-5p chr8 27701690 27701711 + hsa-miR-378d chr4 5923279 5923298 - hsa-miR-532-3p chrX 50003204 50003225 + hsa-miR-140-5p chr16 69933103 69933124 + hsa-miR-378e chr5 170028545 170028563 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005899.4 chr17 32328441 32329395 + AC006511.5 chr12 8014093 8019007 - AC007285.1 chr7 29988600 30027543 + AC007906.1 chr16 53168522 53169450 + AC007952.4 chr17 19112000 19112636 - AC010542.4 chr16 66549280 66551189 + AC011503.2 chr19 23927788 23929287 + AC108134.2 chr16 3156736 3157483 - AC132217.1 chr11 2129121 2129964 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL021707.2 chr22 38667585 38681847 - AL022311.1 chr22 37876148 37895563 + AL135925.1 chr10 79825902 79827602 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 26786760 Title: Plasma extracellular RNA profiles in healthy and cancer patients Author: Yuan T, Huang X, Woodcock M, Du M, Dittmar R, Wang Y, Tsai S, Kohli M, Boardman L, Patel T, Wang L Journal: Sci Rep. 2016 Jan 20;6:19413. Description: we performed RNA sequencing analysis on plasma extracellular vesicles derived from 50 healthy individuals and 142 cancer patients.